Clinical Trials
Sponsor:
Sponsor Study ID:
Study Title:
A Phase 1/2 Open label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation (PYNNACLE)
NCT Number:
NCT04585750
Phase:
I/II
Protocol Type:
Treatment
Age Group:
Adults
Disease Sites:
Lip, Oral Cavity and Pharynx, Esophagus, Stomach, Colon, Pancreas, Larynx, Lung, Soft Tissue, Ovary, Prostate, Thyroid, Breast
Study Objectives:
This study will assess the safety and tolerability of multiple dose levels of PC14586 in participants with advanced solid tumors containing a p53 Y220C mutation.
Study Documents
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