Sponsor: Alliance for Clinical Trials in Oncology
Sponsor Study ID: A022104
Study Title: The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing the Efficacy of Triplet versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients with Locally Advanced Rectal Cancer
CTO #: 103847
NCT Number: NCT05610163
Phase: II
Protocol Type: Treatment
Age Group: Adults
Disease Sites: Anus; Rectum
Study Objectives: To evaluate and compare the cCR rates in patients with locally advanced rectal cancer treated with neoadjuvant LCRT followed by neoadjuvant mFOLFIRINOX versus neoadjuvant LCRT followed by neoadjuvant mFOLFOX6.