Radiation Oncology - about the program

Radiation Oncology

As part of MUSC Hollings Cancer Center, South Carolina's only NCI Designated Cancer Center, the MUSC Health Radiation Oncology team is committed to providing the best evidence-based care.

Patients are often faced with a difficult decision regarding cancer treatment using surgery, chemotherapy or radiation therapy. Using our multidisciplinary approach to cancer care, we will work to determine the best treatment recommendations and deliver the highest quality care. Our staff of physicians, nurses, physicists, dosimetrists, therapists and clinical support staff are ready to answer any questions you have. Welcome and thank you for allowing us to participate in your care.

Conditions We Treat

The MUSC Health radiation oncology team treats a variety of tumors and cancer types, as well as certain other conditions, in virtually any area of the body. Keep in mind each of these conditions often has several treatment options, all of which carry their own associated risks. Many things are considered when determining the best treatment for your individual diagnosis, so talk to your doctor about your options.

Breast Cancer

Comprehensive Breast Care Program provides a patient centered treatment experience which incorporates the latest technology to optimize breast cancer outcomes while lowering the potential risks of treatment. We utilize a specialized technique known as Deep Inspiration Breath Hold to minimize radiation exposure to the heart during breast radiotherapy. In this procedure patients can simply take in a deep breath, thereby filling the lungs with air, and effectively displace the heart away from the breast. This technique is routinely used for patients with left-sided breast cancers as the heart is predominantly positioned in the left side of the chest.

Gastrointestinal Cancers

Colorectal cancer is the second leading cause of cancer-related deaths in South Carolina, claiming residents at a higher rate than in the nation as a whole. Our state also ranks among the nation’s highest for pancreatic cancer. To combat these prevalent diseases, the Gastrointestinal Cancer Program at MUSC diagnoses and treats cancers of the esophagus, stomach, pancreas, liver, biliary tree, colon and rectum. Advanced radiation oncology treatments include tomotherapy, a highly accurate radiation therapy that allows the radiation oncologist to image and treat a patient in the same setting, minimizing toxicity.

Gynecologic Cancers

With South Carolina ranked ninth in the nation in cervical cancer deaths, the advanced diagnostics and treatments available at MUSC Hollings Cancer Center are a source of hope to thousands of women. Our Gynecologic Cancer Program encompasses all aspects of diagnosis, surgery, treatment and management of cervical, endometrial, ovarian, uterine and vulvar cancer. Our specialized radiation oncology services offer targeted therapy and decreased side effects.

Head & Neck Cancers

Collaboration through multidisciplinary care is the hallmark of our Head & Neck Tumor Center, with more than 30 specialists available to consult on the best course of treatment and rehabilitative options. We treat most head and neck cancers, including tumors in the neck, mouth, thyroid, throat/larynx, pituitary gland, saliva glands, ear, eye and nose. The state-of-the-art radiation therapy options include Tomotherapy and our Gamma Knife Center.

Lung and Thoracic Cancers

The MUSC Lung and Thoracic Cancers Program focuses on the treatment of lung and esophageal cancer, Barrett's Esophagus, chest wall tumors and mediastinal tumors. We offer state-of-the-art radiation oncology expertise, including PET/CT scan fusion for more accurate radiation planning and stereotactic radiosurgery with the TrueBeam STx for medically inoperable patients.


MUSC's Jenny Sullivan Sanford Melanoma & Skin Cancer Program is the only program dedicated to advanced melanoma care in South Carolina. MUSC’s program has been designated a Melanoma Center of Excellence (MCE) by the Melanoma Hope Network — one of fewer than 20 programs with this designation in the United States. Our radiation oncology treatments for melanoma include the Gamma Knife Center, Intensity Modulated Radiation Therapy (IMRT), tomotherapy and brachytherapy for temporary radiation implants.

Neurological Cancers

MUSC Health's Brain & Spine Tumor Program is a collaboration between Hollings Cancer Center and the MUSC Neurosciences team. Our program offers the latest in radiation oncology treatments for patients with tumors of the brain and spine, including the only Gamma Knife Center in the lowcountry.

Pediatric Cancers

Ranked among the nation’s top pediatric facilities, MUSC Children’s Hospital is known for its exceptional dedication to caring for children and adolescents with cancer. The MUSC Pediatric Cancer Program is part of the Pediatric Hematology/Oncology Unit at MUSC Children’s Hospital, South Carolina’s most comprehensive pediatric healthcare center. We bring together leading experts from radiation oncology and other oncology specialties to offer the most comprehensive care available anywhere.

Prostate and Genitourinary Cancers

The Prostate and Genitourinary Cancer Program at Hollings Cancer Center is recognized as a regional leader in the treatment of genitourinary cancers, including cancers of the prostate, bladder, kidney, adrenal system, penis and testes. Our radiation oncology team uses targeted tumor ablation — such as cryotherapy, radio frequency ablation and brachytherapy — to kill tumors in their current location while preserving surrounding tissue.


MUSC Health's Sarcoma Program is well-known and respected throughout the country — we’re one of a small number of healthcare centers offering focused sarcoma care. With only an estimated 11,000 new cases of sarcoma diagnosed in the United States each year, it is imperative that patients are treated at a center with a team of physicians experienced in this disease. This ensures that patients get an accurate diagnosis, timely staging and appropriate treatment.

Radiation Oncology Care Team

In collaboration with MUSC Hollings Cancer Center, our team includes some of the region’s most knowledgeable and dedicated cancer specialists.

Our center uses a team approach in which our medical experts collaborate to develop a customized treatment plan for your specific case. Team members may include a surgeon, radiation oncologist, medical oncologist, medical physicist, nurse, radiation therapist and other experts at our center.

Radiation Oncology Treatment Options

MUSC Health Radiation Oncology has a wide variety of modern technology enabling us to treat our patients with leading-edge techniques, advanced clinical protocols and the latest in innovative research and clinical trials.

Additional radiation oncology options at MUSC Health include:

  • Intensity Modulated Radiotherapy (IMRT)
  • High Dose Rate(HDR) Brachytherapy
  • Low Dose Rate (LDR) Brachytherapy
  • Intravascular Brachytherapy
  • Prostate Seed Implant
  • Stereotactic Body Radiation Therapy (SBRT)
  • Total Body Irradiation

Radiation Oncology Patient Guide

Request an appointment at MUSC Health Radiation Oncology to begin the process of determining whether you’re a candidate for treatment. We’ll talk to you about your diagnosis and insurance coverage, so it’s best to have your insurance information ready.

Based on the initial conversation, we’ll schedule a personal consultation within the following two to four days. You’ll meet with a member of our physician team and a decision will be made on whether treatment is right for you.

We'll guide you through the remaining steps, including:

Prostate Cancer Low-Risk

Prostate Cancer Intermediate-Risk

Prostate Cancer High-Risk


MUSC Radiation Oncology

169 Ashley Avenue
Charleston, SC 29425
843-792-5472 - fax
Parking: Valet service available ($5/day) or use the Jonathan Lucas Garage

Hollings Cancer Center/Downtown

Radiation Oncology Services
86 Jonathan Lucas Street
Charleston, SC 29425
843-792-5472 - fax
Parking: Valet service available ($5/day) or use the Jonathan Lucas Garage

Hollings Cancer Center/Mount Pleasant

Radiation Oncology Services
1180 Hospital Drive
Mount Pleasant, SC 29464
843-849-3628 - fax

MUSC Health Tidelands Health Radiation Therapy Center

Waccamaw Medical Park East
4033 Highway 17 Bypass, Suite 106
Murrells Inlet, SC 29440
843-545-5660 - fax

Contact Us

For more information, you may contact us at 843-792-3271 and a member of our staff will discuss your information with our physicians and determine the best next step for your individual needs.

Information for Referring Physicians

Mailing Address:

MUSC Health Radiation Oncology
169 Ashley Avenue
PO Box 250318
Charleston, SC 29425
843-792-5472 - fax

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