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• STUDY12721
  
  Computerized Cognitive Training for Pediatric Brain Tumor Patients: A Pilot Study
  
  This randomized clinical trial studies how well an adaptive computerized cognitive training program works compared to a non-adaptive computerized cognitive training program in treating younger patients with brain tumor who underwent radiation therapy. Providing a computer training program may improve the well-being and quality of life of patients with cognitive (physical and mental) function difficulties caused by radiation therapy to the brain.
  
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• STUDY13473
  
  Randomized Controlled Trial of Olanzapine for the Control of Chemotherapy induced Vomiting in Children Receiving Highly Emetogenic Chemotherapy
  
  Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents. Most children receiving hematopoietic stem cell transplant (HSCT) conditioning experience CINV despite receiving antiemetic prophylaxis. Olanzapine improves CINV control in adult cancer patients, has a track record of safe use in children with psychiatric illness, does not interact with chemotherapy and is inexpensive. We hypothesize that the addition of olanzapine to standard antiemetics will improve chemotherapy-induced vomiting (CIV) control in children receiving high dose cyclophosphamide for hematopoietic stem cell transplantation (HSCT) conditioning.
  
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• STUDY13604B
  
  A Single-Site, Parallel-Group, Randomized-Controlled Trial of Navigation A Versus Usual Care for The Management of Delays and Racial Disparities Starting Postoperative Radiation Therapy in Adults with Surgically-Managed, Locally Advanced Head and Neck Squamous Cell Carcinoma (NDURE 2.0)
  
  To assess the acceptability of NDURE to white and AA HNSCC patients and HNSCC providers. To determine the feasibility of a single dedicated navigator to manage a caseload of patients for the NDURE intervention. To evaluate the feasibility of collecting pre- and post-NDURE intervention outcome measures in this patient population.
  
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• STUDY15667
  
  Implementation and Effectiveness Trial of HN STAR
  
  This trial studies how a computer program, the Head and Neck Survivorship Tool: Assessment and Recommendations (HN-STAR) works in helping health care providers care for survivors of head and neck squamous cell cancer. HN-STAR is a type of survivorship tool that survivors and their health care providers may use together to better manage the survivors' health.
  
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• STUDY16672
  
  Duloxetine to Prevent Oxaliplatin Induced Chemotherapy Induced Peripheral Neuropathy: A Randomized, Double Blind, Placebo Controlled Phase II to Phase III Study
  
  This phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with oxaliplatin in patients with stage II-III colorectal cancer. Duloxetine increases the amount of certain chemicals in the brain that help relieve depression and pain. Giving duloxetine in patients undergoing treatment with oxaliplatin for colorectal cancer may help prevent peripheral neuropathy.
  
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