Brain Cancer Trials
Every treatment that has ever made a difference in cancer care was once a part of a clinical trial. MUSC Hollings Cancer Center is committed to offering the best treatments available today while searching for even better ones for the future. Ask your doctor if a clinical trial is right for you.
STUDY25092
A Phase 3, Open-Label, Randomized 2-arm Study Comparing the Clinical Efficacy and Safety of Niraparib With Temozolomide in Adult Participants With Newly Diagnosed, MGMT Unmethylated Glioblastoma
Test whether niraparib compared with temozolomide significantly extends progression-free survival in participants with newly-diagnosed, MGMT promoter unmethylated glioblastoma. Test whether niraparib compared with temozolomide significantly extends overall survival in participants with newly-diagnosed, MGMT promoter unmethylated glioblastoma.
Study InformationSTUDY25372
Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)
To compare the efficacy and safety of staged stereotactic radiosurgery vs fractionated stereotactic radiotherapy. To compare the safety profile of staged stereotactic radiosurgery vs fractionated stereotactic radiotherapy for large brain metastases
Study Information